Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 2/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18845452 | 0.80 | L3MBTL1 (0.39) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL7701505 | 0.76 | KMT2A (0.57) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL27836981 | 0.73 | TSHR (0.42) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL8536881 | 0.73 | L3MBTL1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL9165581 | 0.73 | L3MBTL1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL1200547 | 0.73 | TSHR (0.42) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL5243353 | 0.73 | L3MBTL1 (0.39) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL9165582 | 0.73 | L3MBTL1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL27191 | 0.65 | ACHE (0.47) | SMN1; SMN2L3MBTL1POLBLMNAKCNH2 | |
| SCHEMBL3992907 | 0.65 | SCN1A (0.55) | MEN1KMT2ASMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958275-A4 | SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 | UNIV VANDERBILT (US) | 2004-12-01 | — | — | EP | claimed |
| EP-0958275-A1 | SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 | VANDERBILT UNIVERSITY (US) | 1999-11-24 | — | — | EP | claimed |
| WO-1998029382-A1 | SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 | VANDERBILT UNIVERSITY (US) | 1998-07-09 | — | — | WO | claimed |