Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301580 | 0.78 | KMT2A (0.52) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL6536090 | 0.76 | MEN1 (0.35) | KMT2AMEN1ALDH1A1TSHRCHRM2 | |
| SCHEMBL465593 | 0.75 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL7225521 | 0.75 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL17729332 | 0.75 | KMT2A (0.53) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL10402999 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL2835326 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL7699172 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL18367774 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 | |
| SCHEMBL7998269 | 0.72 | PTGS2 (0.42) | KMT2AMEN1ALDH1A1CYP3A4PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263429-A1 | ANTIVIRAL THERAPY | Universiteit Utrecht (NL) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001068086-A1 | ANTIVIRAL THERAPY | UNIVERSITEIT UTRECHT (NL) | 2001-09-20 | — | — | WO | disclosed |