Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536173 | 0.88 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL6536248 | 0.82 | CA1 (0.33) | ALDH1A1 | |
| SCHEMBL6535991 | 0.78 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL6536227 | 0.78 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL6536124 | 0.76 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL6536329 | 0.61 | CACNA1D (0.35) | ADORA3TSHRALDH1A1CACNA1D | |
| SCHEMBL4752286 | 0.59 | POLB (0.31) | — | |
| SCHEMBL31558897 | 0.55 | CACNA1D (0.32) | TSHRCACNA1D | |
| SCHEMBL4591483 | 0.54 | ADORA3 (0.35) | ADORA3TSHRALDH1A1 | |
| SCHEMBL9616757 | 0.54 | ADORA3 (0.41) | ADORA3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425015-A4 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1425015-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003015715-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |