Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145020 | 0.84 | MAPT (0.41) | ADORA3TSHRMAPTHTTKMT2A | |
| SCHEMBL14968287 | 0.76 | MAPT (0.41) | ADORA3TSHRMAPTHTTAURKA | |
| SCHEMBL7147343 | 0.74 | TSHR (0.39) | ADORA3TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL9358496 | 0.74 | TSHR (0.39) | ADORA3TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL14968052 | 0.73 | HTT (0.45) | MAPTHTTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL14968177 | 0.71 | CYP3A4 (0.51) | MAPTHTTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL11448271 | 0.71 | TSHR (0.50) | ADORA3TSHRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11435892 | 0.70 | NPSR1 (0.44) | ADORA3TSHRMAPTHTTKMT2A | |
| SCHEMBL57714 | 0.70 | TSHR (0.49) | ADORA3TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL14967143 | 0.69 | TSHR (0.48) | ADORA3TSHRKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440723-A4 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | — | 1992-05-20 | — | — | EP | disclosed |
| EP-0440723-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS. | SEPRACOR INC (US) | 1991-08-14 | — | — | EP | disclosed |
| WO-1990004643-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCIDATE ESTERS | SEPRACOR, INC. (US) | 1990-05-03 | — | — | WO | disclosed |