Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649818 | 0.59 | ERN1 (0.48) | PRKDCALDH1A1 | |
| SCHEMBL10972522 | 0.59 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1199234 | 0.58 | — | — | |
| SCHEMBL7811222 | 0.57 | ALDH1A3 (0.42) | PRKDCALDH1A1 | |
| SCHEMBL304092 | 0.57 | ERN1 (0.41) | PRKDCALDH1A1SMN1; SMN2 | |
| SCHEMBL568791 | 0.56 | — | — | |
| SCHEMBL14269815 | 0.56 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10018128 | 0.56 | PRKDC (0.54) | PRKDCALDH1A1SMN1; SMN2 | |
| SCHEMBL18382141 | 0.56 | PRKDC (0.54) | PRKDCALDH1A1SMN1; SMN2 | |
| SCHEMBL12584035 | 0.55 | PRKDC (0.42) | PRKDCALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425015-A4 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1425015-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003015715-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |