Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15370277 | 0.88 | SRC (0.41) | ALDH1A3ALDH1A1ALDH3A1CYP2A6MAPK1 | |
| SCHEMBL22490227 | 0.84 | ALDH1A3 (0.37) | ALDH1A3ALDH1A1ALDH3A1CYP2A6MAPK1 | |
| SCHEMBL19317368 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPK1PRKDCGAATSHR | |
| SCHEMBL22120279 | 0.80 | ALDH1A3 (0.34) | ALDH1A3ALDH1A1ALDH3A1CYP2A6MAPK1 | |
| SCHEMBL22452371 | 0.78 | SRC (0.41) | ALDH1A3ALDH1A1ALDH3A1CYP2A6MAPK1 | |
| SCHEMBL22120150 | 0.78 | ALDH1A1 (0.42) | ALDH1A3ALDH1A1ALDH3A1MAPK1SRC | |
| SCHEMBL7814448 | 0.78 | APEX1 (0.45) | ALDH1A3ALDH1A1ALDH3A1CYP2A6MAPK1 | |
| SCHEMBL548045 | 0.76 | ERN1 (0.42) | ALDH1A3ALDH1A1CYP2A6SRCPRKDC | |
| SCHEMBL154851 | 0.75 | ALDH1A3 (0.53) | ALDH1A3ALDH1A1ALDH3A1CYP2A6TSHR | |
| SCHEMBL12552996 | 0.75 | ERN1 (0.44) | ALDH1A3SRCGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11913944-B2 | Photoaffinity probes | PROMEGA CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-20200340982-A1 | PHOTOAFFINITY PROBES | PROMEGA CORPORATION | 2020-10-29 | — | — | US | disclosed |
| WO-2020191339-A1 | PHOTOAFFINITY PROBES | PROMEGA CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |
| US-6320051-B1 | AMINO(NH) OR OXYGEN(O) SUBSTITUTED, ENZYME INHIBITORS OF STAPHLOCCOCUS AUREUS METHIONYL T-RNA SYNTHETASE (MRS); ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-20 | — | — | US | disclosed |
| EP-1084110-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999055677-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 1999-11-04 | — | — | WO | disclosed |