SCHEMBL6536402

SCHEMBL6536402

CCC(C)NC(=O)NS(=O)(=O)c1cccc(Cl)c1S(=O)(=O)N(C)C

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CCR6 P51684 4/20 0.37
GAA P10253 1/20 0.37
NR1H4 Q96RI1 1/20 0.36
CXCR1 P25024 1/20 0.36
CXCR2 P25025 1/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536403 0.80 FBP1 (0.50) LMNAALDH1A1
SCHEMBL10726151 0.70 FBP1 (0.50) LMNAALDH1A1
SCHEMBL19627376 0.69 POLB (0.50) CA12CA1CA2CA9GAA
SCHEMBL10724941 0.68 MCOLN3 (0.45) CCR6CXCR1CXCR2POLBLMNA
SCHEMBL20387787 0.67 PKM (0.54) GAAALDH1A1KMT2A
SCHEMBL23467914 0.66 GAA (0.69) CA12CA1CA2CA9GAA
SCHEMBL9305036 0.65 GAA (0.50) CA12CA1CA2CA9GAA
SCHEMBL8890921 0.65 CA12 (0.45) CA12CA1CA2CA9GAA
SCHEMBL19629830 0.64 CA12 (0.57) CA12CA1CA2CA9POLB
SCHEMBL30168123 0.64 CXCR1 (0.44) CCR6CXCR1CXCR2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1011311-A4 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE EXSEED GENETICS L L C (US) 2004-05-26 EP claimed
EP-1011311-A1 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE Exseed Genetics L.L.C. (US) 2000-06-28 EP claimed
WO-1999007211-A9 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE EXSEED GENETICS L L C (US) 1999-04-29 WO claimed
WO-1999007211-A1 CONTROLLED GERMINATION USING INDUCIBLE PHYTATE GENE EXSEED GENETICS, L.L.C. (US) 1999-02-18 WO claimed
US-5608143-A NUCLEIC ACID PROMOTER FRAGMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-04 US claimed
US-5364780-A Genetic engineering with DNA and promoters E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-15 US claimed
EP-0463056-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP claimed
WO-1990011361-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-04 WO claimed
EP-0388186-A1 External regulation of gene expression E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-19 EP claimed
US-5608143-A NUCLEIC ACID PROMOTER FRAGMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-04 US disclosed
US-5364780-A Genetic engineering with DNA and promoters E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-15 US disclosed
EP-0463056-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP disclosed
WO-1990011361-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-04 WO disclosed
EP-0388186-A1 External regulation of gene expression E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-19 EP disclosed