Styrene

Styrene

SCHEMBL6536677

C=C(C)c1cccc(C(C)(C)N=C=O)c1.C=Cc1ccccc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 4/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
PAX8 Q06710 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALPL P05186 1/20 0.36
GLA P06280 1/20 0.36
ALPI P09923 1/20 0.36
ALPG P10696 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402461 0.88 L3MBTL1 (0.48) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
SCHEMBL149072 0.88 L3MBTL1 (0.48) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
SCHEMBL1278395 0.84 L3MBTL1 (0.45) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
Carbimide SCHEMBL5615872 0.84 L3MBTL1 (0.45) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
SCHEMBL10416073 0.83 L3MBTL1 (0.44) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
SCHEMBL4956834 0.81 TP53 (0.42) TSHRALDH1A1
SCHEMBL12614391 0.79 L3MBTL1 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
SCHEMBL29815911 0.77 L3MBTL1 (0.47) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
SCHEMBL5598556 0.77 L3MBTL1 (0.47) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1
Styrene SCHEMBL1171199 0.77 ALDH1A1 (0.54) CYP1A2CYP2D6CYP2C9CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1303559-A4 ACTIVATED MODULAR GRAFTED POLYMERIC SURFACES MIMOTOPES PTY LTD (AU) 2004-06-30 EP claimed
US-20040076623-A1 Activated modular grafted polymeric surfaces MIMOTOPES PTY LTD (AU) 2004-04-22 US claimed
EP-1303559-A1 ACTIVATED MODULAR GRAFTED POLYMERIC SURFACES Mimotopes Pty Ltd (AU) 2003-04-23 EP claimed
WO-2002006384-A1 ACTIVATED MODULAR GRAFTED POLYMERIC SURFACES MIMOTOPES PTY LTD (AU) 2002-01-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040076623-A1 Activated modular grafted polymeric surfaces SIGLEC7, PHAX, STUB1 CYP1A2 4766/4885CYP2D6 4622/4885CYP2C9 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.