SCHEMBL653671

SCHEMBL653671

O=c1oc2ccc[c]c2c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
KDM4E B2RXH2 5/20 0.44
GAA P10253 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
KMT2A Q03164 3/20 0.43
RXFP1 Q9HBX9 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MAPK1 P28482 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 4/20 0.42
HSD17B10 Q99714 2/20 0.42
MAOA P21397 2/20 0.42
CYP3A4 P08684 2/20 0.42
GLA P06280 2/20 0.42
HPGD P15428 1/20 0.42
PGAM1 P18669 1/20 0.42
CASP1 P29466 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11172224 0.87 KDM4E (0.47) ALDH1A1KDM4EGAASMN1; SMN2NPSR1
SCHEMBL5099 0.79 MAOA (0.48) ALDH1A1KDM4EGAASMN1; SMN2KMT2A
SCHEMBL654268 0.77 MAOA (0.63) ALDH1A1KDM4EGAASMN1; SMN2KMT2A
SCHEMBL29709713 0.74 KMT2A (0.62) ALDH1A1KDM4EGAASMN1; SMN2NPSR1
SCHEMBL304367 0.74 KMT2A (0.62) ALDH1A1KDM4EGAASMN1; SMN2NPSR1
SCHEMBL29416517 0.74 KMT2A (0.62) ALDH1A1KDM4EGAASMN1; SMN2NPSR1
SCHEMBL10507038 0.74 SMN1; SMN2 (0.53) ALDH1A1KDM4EGAASMN1; SMN2NPSR1
SCHEMBL2409495 0.73 CYP2A6 (0.33) ALDH1A1SMN1; SMN2TDP1HSD17B10CYP3A4
Water SCHEMBL28602073 0.73 KMT2A (0.60) ALDH1A1KDM4EGAASMN1; SMN2NPSR1
SCHEMBL10025828 0.73 L3MBTL1 (0.60) ALDH1A1KDM4EGAASMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1658081-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA Bioscience nv (BE) 2006-05-24 EP claimed
WO-2005021003-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA BIOSCIENCE NV (BE) 2005-03-10 WO claimed
US-20040077859-A1 Immunosuppressive effects of pteridine derivatives 4 AZA BIOSCIENCE NV (BE) 2004-04-22 US claimed
US-5554735-A Azo oxime ethers and their use as fungicides CIBA-GEIGY CORPORATION (US) 1996-09-10 US claimed
EP-0628027-A1 AZO OXIME ETHERS AND THEIR USE AS FUNGICIDES CIBA-GEIGY AG (CH) 1994-12-14 EP claimed
WO-1993016986-A1 AZO OXIME ETHERS AND THEIR USE AS FUNGICIDES CIBA-GEIGY AG (CH) 1993-09-02 WO claimed
US-5216146-A 2-benzocoumarinyl-carbapenems MERCK & CO., INC. (US) 1993-06-01 US claimed
EP-0515232-A1 2-benzocoumarinyl-carbapenems MERCK & CO. INC. (US) 1992-11-25 EP claimed
US-20240231224-A9 HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF LAM RESEARCH CORPORATION 2024-07-11 US disclosed
WO-2024137876-A2 SURFACE MODIFICATION OF METAL CATALYSTS WITH HYDROPHOBIC LIGANDS OR IONOMERS TWELVE BENEFIT CORPORATION (US) 2024-06-27 WO disclosed
US-20240200208-A1 CO2 PURIFICATION AND REDUCTION SYSTEMS SUMITOMO MITSUI BANKING CORPORATION 2024-06-20 US disclosed
WO-2024123514-A1 CO2 PURIFICATION AND REDUCTION SYSTEMS TWELVE BENEFIT CORPORATION (US) 2024-06-13 WO disclosed
US-20240192590-A1 APPARATUS AND PROCESS FOR EUV DRY RESIST SENSITIZATION BY GAS PHASE INFUSION OF A SENSITIZER LAM RESEARCH CORPORATION 2024-06-13 US disclosed
WO-2024108304-A1 DITHIOL CHELATORS FOR METAL CONJUGATION TO ANTIBODIES STANDARD BIOTOOLS CANADA INC. (CA) 2024-05-30 WO disclosed
US-5216146-A 2-benzocoumarinyl-carbapenems MERCK & CO., INC. (US) 1993-06-01 US disclosed
US-5182384-A Chemical intermediates for bactericides MERCK & CO., INC. (US) 1993-01-26 US disclosed
EP-0515232-A1 2-benzocoumarinyl-carbapenems MERCK & CO. INC. (US) 1992-11-25 EP disclosed
EP-0515217-A1 2-Benzocoumarinyl carbapenems MERCK & CO. INC. (US) 1992-11-25 EP disclosed
US-5162314-A 2-benzocoumarinyl carbapenems MERCK & CO., INC. (US) 1992-11-10 US disclosed
US-5153186-A Antibiotics for methicillin resistant Staphylococcus strains MERCK & CO., INC. (US) 1992-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077859-A1 Immunosuppressive effects of pteridine derivatives TPMT, NFATC1, MALT1 ALDH1A1 1257/4885KDM4E 2108/4885GAA 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.