Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757979 | 0.82 | — | — | |
| SCHEMBL6536732 | 0.75 | KCNA3 (0.32) | MEN1LMNAKMT2ANPSR1HSD17B10 | |
| SCHEMBL3115530 | 0.73 | — | — | |
| SCHEMBL5543160 | 0.72 | IDO1 (0.44) | — | |
| SCHEMBL5540903 | 0.71 | NAAA (0.44) | MAPT | |
| SCHEMBL5256662 | 0.71 | NAAA (0.44) | MAPT | |
| SCHEMBL6951988 | 0.71 | NAAA (0.44) | MAPT | |
| SCHEMBL6238419 | 0.71 | JAK2 (0.33) | LMNAMAPT | |
| SCHEMBL3161543 | 0.71 | SMN1; SMN2 (0.34) | MEN1LMNAKMT2A | |
| SCHEMBL4629349 | 0.70 | KCNA3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326605-A4 | METHODS FOR INHIBITING PROLIFERATION AND INDUCING APOPTOSIS IN CANCER CELLS | UNIV CREIGHTON (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-1326605-A1 | METHODS FOR INHIBITING PROLIFERATION AND INDUCING APOPTOSIS IN CANCER CELLS | CREIGHTON UNIVERSITY (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2001085166-A1 | METHODS FOR INHIBITING PROLIFERATION AND INDUCING APOPTOSIS IN CANCER CELLS | CREIGHTON UNIVERSITY (US) | 2001-11-15 | — | — | WO | disclosed |