Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728235 | 0.94 | BCHE (0.59) | BCHEKCNH2SIGMAR1OPRM1CHRM2 | |
| SCHEMBL3749579 | 0.86 | OPRK1 (0.59) | BCHESIGMAR1OPRM1HTR1AADRA2A | |
| Bromide SCHEMBL10656516 | 0.85 | OPRK1 (0.57) | BCHESIGMAR1OPRM1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL2831864 | 0.85 | OPRK1 (0.60) | BCHESIGMAR1OPRM1HTR1AADRA2A | |
| SCHEMBL11573309 | 0.82 | OPRK1 (0.64) | BCHESIGMAR1OPRM1HTR1AADRA2A | |
| SCHEMBL6706300 | 0.82 | KCNH2 (0.66) | KCNH2SIGMAR1OPRM1CHRM2HTR1A | |
| SCHEMBL7594151 | 0.80 | TDP1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10662405 | 0.80 | SIGMAR1 (0.69) | KCNH2SIGMAR1OPRM1CHRM2HTR1A | |
| SCHEMBL11699577 | 0.80 | SIGMAR1 (0.69) | KCNH2SIGMAR1OPRM1CHRM2HTR1A | |
| SCHEMBL2364160 | 0.77 | BCHE (0.49) | BCHESIGMAR1OPRM1HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009440-A4 | METHOD FOR INHIBITING IMMUNOSTIMULATORY DNA ASSOCIATED RESPONSES | MACFARLANE DONALD E (US) | 2004-03-17 | — | — | EP | claimed |
| US-20030232856-A1 | Methods for inhibiting immunostimulatory DNA associated responses | MACFARLANE DONALD E (US) | 2003-12-18 | — | — | US | claimed |
| US-20020151564-A1 | Methods for inhibiting immunostimulatory DNA associated responses | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2002-10-17 | — | — | US | claimed |
| US-6399630-B1 | 2-ALKOXY-6-HALO-9-AMINOACRIDINES; BLOCKING ANTI-APOPTOTIC EFFECT OF CPG-ODN AND CPG-ODN-INDUCED SECRETION OF IL-6; HIGHLY SPECIFIC; AUTOIMMUNE DISEASE, ARTHRITIS, LUPUS, INFLAMMATORY BOWEL DISEASE | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2002-06-04 | — | — | US | claimed |
| EP-1009440-A1 | METHOD FOR INHIBITING IMMUNOSTIMULATORY DNA ASSOCIATED RESPONSES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1999001154-A1 | METHOD FOR INHIBITING IMMUNOSTIMULATORY DNA ASSOCIATED RESPONSES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1999-01-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151564-A1 | Methods for inhibiting immunostimulatory DNA associated responses | IRF3, STING1, DNA2 | BCHE 4414/4885KCNH2 4034/4885SIGMAR1 4657/4885 |
| US-20030232856-A1 | Methods for inhibiting immunostimulatory DNA associated responses | IRF3, STING1, DNA2 | BCHE 4414/4885KCNH2 4034/4885SIGMAR1 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.