SCHEMBL6537039

SCHEMBL6537039

CCO[Si](CCCNC(=O)OC)(OC)OC

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
ACHE P22303 13/20 0.39
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477710 0.96 EPHX1 (0.52) EPHX1ACHECA12CA1CA2
SCHEMBL3401549 0.93 EPHX1 (0.55) EPHX1ACHECA12CA1CA2
SCHEMBL3839523 0.87 EPHX1 (0.58) EPHX1ACHECA12CA1CA2
SCHEMBL467687 0.87 EPHX1 (0.55) EPHX1ACHE
SCHEMBL16248012 0.86 ACHE (0.44) EPHX1ACHE
SCHEMBL5916534 0.86 EPHX1 (0.61) EPHX1ACHE
SCHEMBL5916617 0.86 EPHX1 (0.61) EPHX1ACHE
SCHEMBL28299554 0.85 EPHX1 (0.53) EPHX1ACHE
SCHEMBL5916544 0.85 EPHX1 (0.47) EPHX1ACHE
SCHEMBL728329 0.84 EPHX1 (0.34) EPHX1ACHECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6673954-B1 REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST GENERAL ELECTRIC COMPANY 2004-01-06 US claimed
EP-3169690-B1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2018-12-05 EP disclosed
US-9663539-B2 Process for producing low-color and color-stable isocyanatoorganosilanes and products derived therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US disclosed
EP-3169690-A1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM Momentive Performance Materials Inc. (US) 2017-05-24 EP disclosed
WO-2016010900-A1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-01-21 WO disclosed
US-20160009738-A1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2016-01-14 US disclosed
US-6673954-B1 REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST GENERAL ELECTRIC COMPANY 2004-01-06 US disclosed