SCHEMBL3401549

SCHEMBL3401549

CCO[Si](CCCNC(=O)OC)(OCC)OCC

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.55
ACHE P22303 14/20 0.41
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839523 0.94 EPHX1 (0.58) EPHX1ACHECA12CA1CA2
SCHEMBL5916617 0.93 EPHX1 (0.61) EPHX1ACHE
SCHEMBL6537039 0.93 EPHX1 (0.52) EPHX1ACHECA12CA1CA2
SCHEMBL5916534 0.93 EPHX1 (0.61) EPHX1ACHE
SCHEMBL3477710 0.93 EPHX1 (0.52) EPHX1ACHECA12CA1CA2
SCHEMBL5916829 0.88 EPHX1 (0.48) EPHX1ACHE
SCHEMBL5916544 0.88 EPHX1 (0.47) EPHX1ACHE
SCHEMBL139102 0.87 ACHE (0.48) EPHX1ACHE
SCHEMBL5916778 0.86 EPHX1 (0.49) EPHX1ACHE
SCHEMBL809069 0.85 ACHE (0.61) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP claimed
US-20130079449-A1 Polymer Composition and Method SOLVAY SA (BE) 2013-03-28 US claimed
WO-2013043321-A1 POLYMER COMPOSITION AND METHOD CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-03-28 WO claimed
CN-101189246-B Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MAT INC 2012-08-08 CN claimed
CN-101189247-B Process for preparing silylisocyanurate MOMENTIVE PERFORMANCE MAT INC 2012-04-11 CN claimed
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US claimed
EP-1869058-B1 PROCESS FOR MAKING SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-12-16 EP claimed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP claimed
CN-101268087-A Method for production of isocyanatosilanes MOMENTIVE PERFORMANCE MAT INC (US) 2008-09-17 CN claimed
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP claimed
CN-101189246-A Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MAT INC (US) 2008-05-28 CN claimed
CN-101189247-A Process for making silylisocyanurate MOMENTIVE PERFORMANCE MAT INC (US) 2008-05-28 CN claimed
EP-1885731-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE Momentive Performance Materials Inc. (US) 2008-02-13 EP claimed
EP-1869058-A2 PROCESS FOR MAKING SILYLISOCYANURATE General Electric Company (US) 2007-12-26 EP claimed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO claimed
WO-2006132799-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-12-14 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
WO-2006113182-A2 PROCESS FOR MAKING SILYLISOCYANURATE GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO claimed
US-20060235221-A1 Process for making silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. 2006-10-19 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235221-A1 Process for making silylisocyanurate PCMT1, SRM, STOM EPHX1 4442/4885ACHE 1265/4885CA12 114/4885
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 EPHX1 4685/4885ACHE 1637/4885CA12 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.