SCHEMBL6537076

SCHEMBL6537076

CCO[Si](CCCNC(=O)Oc1cccc(OC(=O)O)c1C(C)(C)C)(OCC)OCC

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 1/20 0.36
ALDH1A1 P00352 1/20 0.35
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1169021 0.78 HCRTR1 (0.40) NCEH1
SCHEMBL2262830 0.77 P2RY1 (0.34) ALDH1A1BCHEACHE
SCHEMBL16919356 0.76 NPC1 (0.48)
SCHEMBL11217622 0.75 HSP90AA1 (0.52) ALDH1A1
SCHEMBL17745069 0.73 BCHE (0.31) BCHEACHE
SCHEMBL6389685 0.72 MGLL (0.41) ALDH1A1
SCHEMBL6555053 0.71 TDP1 (0.34) NCEH1ALDH1A1
SCHEMBL1546308 0.71 MGLL (0.52) ALDH1A1
SCHEMBL29736740 0.71 NAAA (0.38) BCHE
SCHEMBL1546349 0.70 KMT2A (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6673954-B1 REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST GENERAL ELECTRIC COMPANY 2004-01-06 US claimed
EP-3169690-B1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2018-12-05 EP disclosed
US-9663539-B2 Process for producing low-color and color-stable isocyanatoorganosilanes and products derived therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US disclosed
EP-3169690-A1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM Momentive Performance Materials Inc. (US) 2017-05-24 EP disclosed
WO-2016010900-A1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-01-21 WO disclosed
US-20160009738-A1 PROCESS FOR PRODUCING LOW-COLOR AND COLOR-STABLE ISOCYANATOORGANOSILANES AND PRODUCTS DERIVED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2016-01-14 US disclosed
US-6673954-B1 REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST GENERAL ELECTRIC COMPANY 2004-01-06 US disclosed