SCHEMBL6537096

SCHEMBL6537096

C1=Cc2c(cccc3cccc2-3)C1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
HTR1A P08908 2/20 0.30
HTR7 P34969 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319986 0.96 PRCP (0.40) PRCPCA1CA2HTR1AHTR7
SCHEMBL28424140 0.94 PRCP (0.39) PRCPCA1CA2HTR1AHTR7
SCHEMBL5348620 0.92 PRCP (0.38) PRCPHTR1AHTR7
Hydrochloric Acid SCHEMBL29771714 0.92 PRCP (0.38) PRCPHTR1AHTR7
Propane SCHEMBL28734524 0.89 HTR7 (0.37) PRCPHTR1AHTR7
SCHEMBL28834278 0.89 PRCP (0.36) PRCPCA1CA2HTR1AHTR7
SCHEMBL26606283 0.89 CA1 (0.34) CA1CA2MAOAMAOB
SCHEMBL5356144 0.88 PRCP (0.38) PRCPHTR1AHTR7
SCHEMBL29767639 0.88 PRCP (0.38) PRCPHTR1AHTR7
SCHEMBL15863965 0.87 HTR1A (0.39) MAOBHTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6774078-B1 COMPLEX INCORPORATES A GROUP 3-10 TRANSITION METAL AND AN ANNULATED CYCLOPENTADIENYL LIGAND THAT IS PI-BONDED TO THE METAL EQUISTAR CHEMICALS, LP 2004-08-10 US disclosed