SCHEMBL319986

SCHEMBL319986

C1=Cc2c(cccc2-c2ccccc2)C1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.40
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPK1 P28482 1/20 0.35
HTR1A P08908 2/20 0.35
HTR7 P34969 2/20 0.35
ANPEP P15144 2/20 0.34
KDR P35968 1/20 0.34
IL1RN P18510 1/20 0.34
ERAP2 Q6P179 1/20 0.34
ERAP1 Q9NZ08 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
PARP10 Q53GL7 1/20 0.33
PARP11 Q9NR21 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424140 0.98 PRCP (0.39) PRCPALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL5348620 0.96 PRCP (0.38) PRCPALDH1A1HSD17B10HPGDBCL2L1
Hydrochloric Acid SCHEMBL29771714 0.96 PRCP (0.38) PRCPALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL6537096 0.96 PRCP (0.34) PRCPHTR1AHTR7CA1CA2
Propane SCHEMBL28734524 0.93 HTR7 (0.37) PRCPHTR1AHTR7
SCHEMBL28834278 0.93 PRCP (0.36) PRCPALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29767639 0.92 PRCP (0.38) PRCPALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL5356144 0.92 PRCP (0.38) PRCPALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL5350419 0.89 PTGER1 (0.37) PRCPALDH1A1HTR1AHTR7
SCHEMBL6652499 0.88 ALDH1A1 (0.47) PRCPALDH1A1HPGDMAPK1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746224-B2 Heterophasic polypropylene with propylene hexene random copolymer as matrix BOREALIS AG (AT) 2023-09-05 US claimed
CN-111989364-B Heterophasic polypropylene with random propylene-hexene copolymer as matrix 博里利斯股份公司 2023-04-18 CN claimed
EP-3790929-B1 HETEROPHASIC POLYPROPYLENE WITH PROPYLENE HEXENE RANDOM COPOLYMER AS MATRIX BOREALIS AG (AT) 2023-04-12 EP claimed
US-20210253839-A1 HETEROPHASIC POLYPROPYLENE WITH PROPYLENE HEXENE RANDOM COPOLYMER AS MATRIX BOREALIS AG (AT) 2021-08-19 US claimed
EP-3790929-A1 HETEROPHASIC POLYPROPYLENE WITH PROPYLENE HEXENE RANDOM COPOLYMER AS MATRIX Borealis AG (AT) 2021-03-17 EP claimed
CN-111989364-A Heterophasic polypropylene with random propylene-hexene copolymer as matrix 博里利斯股份公司 2020-11-24 CN claimed
WO-2019215156-A1 HETEROPHASIC POLYPROPYLENE WITH PROPYLENE HEXENE RANDOM COPOLYMER AS MATRIX BOREALIS AG (AT) 2019-11-14 WO claimed
US-10030131-B2 Pneumatic object provided with a gastight layer containing a thermoplastic elastomer and a thermoplastic COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-07-24 US claimed
US-9914328-B2 Inflatable object provided with a gas-tight layer containing a thermoplastic elastomer and a hydrocarbon-based resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (CH) 2018-03-13 US claimed
CN-105567258-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly CHI MEI CORP 2016-05-11 CN claimed
CN-1720314-A cyclobutane derivatives MERCK PATENT GMBH (DE) 2006-01-11 CN claimed
CN-1678591-A Novel carboxamide compounds having MCH-antagonistic action, pharmaceutical preparations comprising said compounds and process for their preparation BOEHRINGER INGELHEIM INT (DE) 2005-10-05 CN claimed
CN-1507427-A Indane compounds with negative dielectric anisotropy Ĭ��ר���ɷ����޹�˾ 2004-06-23 CN claimed
CN-1137241-C Liquid crystal composition Ĭ��ר���ɷ����޹�˾ 2004-02-04 CN claimed
CN-1441765-A Chiral compounds II MERCK PATENT GMBH (DE) 2003-09-10 CN claimed
CN-1394862-A Chiral compound MERCK PATENT GMBH (DE) 2003-02-05 CN claimed
CN-1321141-A Decahydronaphthalene derivatives DAINIPPON INK & CHEMICALS (JP) 2001-11-07 CN claimed
CN-1190982-A Liquid crystal composition MERCK PATENT GMBH (DE) 1998-08-19 CN claimed
CN-1178550-A Electro-optical liquid crystal display MERCK PATENT GMBH (DE) 1998-04-08 CN claimed
CN-1036029-A Supertwist-liquid-crystal display (element) MERCK PATENT GMBH (DE) 1989-10-04 CN claimed