SCHEMBL6537211

SCHEMBL6537211

Cc1ccccc1NC(=O)CC(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 1.00
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
HPGD P15428 5/20 0.64
POLB P06746 2/20 0.64
NPC1 O15118 4/20 0.60
ALOX12 P18054 1/20 0.60
ALDH1A1 P00352 3/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
LMNA P02545 2/20 0.57
THRB P10828 1/20 0.57
HDAC3 O15379 1/20 0.55
HDAC4 P56524 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10538897 0.87 RAB9A (0.77) RAB9AMEN1KMT2AHPGDPOLB
SCHEMBL2005846 0.85 RAB9A (0.73) RAB9AMEN1KMT2AHPGDPOLB
SCHEMBL29528561 0.85 RAB9A (0.73) RAB9AMEN1KMT2AHPGDPOLB
SCHEMBL29389339 0.84 RAB9A (0.72) RAB9AMEN1KMT2AHPGDPOLB
SCHEMBL11182704 0.84 RAB9A (0.72) RAB9AMEN1KMT2AHPGDPOLB
SCHEMBL4600276 0.83 RAB9A (0.78) RAB9AMEN1KMT2APOLBNPC1
SCHEMBL382223 0.80 RAB9A (0.67) RAB9AHPGDPOLBNPC1ALOX12
SCHEMBL30065998 0.80 RAB9A (0.67) RAB9AHPGDPOLBNPC1ALOX12
SCHEMBL8772345 0.79 KMT2A (0.70) RAB9AMEN1KMT2AHPGDPOLB
SCHEMBL3315763 0.79 KMT2A (1.00) RAB9AMEN1KMT2AHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824953-B2 POLYMERIZABLE COMPOUND HAVING AN ETHYLENIC UNSATURATED BOND, A METHINE DYE, AND A RADICAL GENERATOR THAT INTERACTS WITH THE DYE TO GENERATE A RADICAL FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
US-20020182530-A1 Polymerizable compound having an ethylenic unsaturated bond, a methine dye, and a radical generator that interacts with the dye to generate a radical FUJI PHOTO FILM CO., LTD. 2002-12-05 US disclosed
EP-0446604-A2 Pyridine and related aza heterocycle derivatives as cardiovascular agents AMERICAN CYANAMID COMPANY (US) 1991-09-18 EP disclosed