SCHEMBL8772345

SCHEMBL8772345

O=C(CC(=O)c1ccccc1)Nc1ccccc1Cl

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.70
ALDH1A1 P00352 5/20 0.70
HPGD P15428 2/20 0.70
RAB9A P51151 5/20 0.66
NPC1 O15118 3/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
MAPT P10636 2/20 0.64
MAPK1 P28482 2/20 0.64
MEN1 O00255 8/20 0.63
POLB P06746 1/20 0.60
GPR55 Q9Y2T6 1/20 0.54
KDM4E B2RXH2 1/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX15 P16050 1/20 0.53
CES1 P23141 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639223 0.87 KMT2A (0.56) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL4395786 0.87 KMT2A (0.60) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL10538897 0.87 RAB9A (0.77) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL9311985 0.85 KMT2A (0.75) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL14440318 0.85 KMT2A (0.53) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL29389982 0.84 KMT2A (0.68) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL17434797 0.84 KMT2A (0.68) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL12010982 0.83 KMT2A (0.67) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL3456977 0.83 ALDH1A1 (1.00) KMT2AALDH1A1HPGDRAB9ANPC1
SCHEMBL11693182 0.82 KMT2A (0.66) KMT2AALDH1A1HPGDRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed