SCHEMBL6537283

SCHEMBL6537283

Cn1c2cc3c(=O)c4c5ccccc5ccc4n(C)c3cc2c(=O)c2c3ccccc3ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
ATM Q13315 2/20 0.44
PIK3CD O00329 1/20 0.42
PIK3CA P42336 1/20 0.42
PIK3CB P42338 1/20 0.42
PIK3CG P48736 1/20 0.42
CA12 O43570 1/20 0.41
BRD4 O60885 1/20 0.41
BRPF1 P55201 1/20 0.41
CA9 Q16790 1/20 0.41
KAT2B Q92831 1/20 0.41
BRD9 Q9H8M2 1/20 0.41
RAB9A P51151 5/20 0.40
KMT2A Q03164 4/20 0.40
NPC1 O15118 4/20 0.40
MEN1 O00255 3/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
CASP1 P29466 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13633669 0.88 HTT (0.61) MAPTHTTATMPIK3CDPIK3CA
SCHEMBL30772964 0.82 GPR3 (0.52) MAPTHTTATMPIK3CDPIK3CA
SCHEMBL10023491 0.82 GPR3 (0.52) MAPTHTTATMPIK3CDPIK3CA
SCHEMBL20987314 0.80 TRPA1 (0.46) MAPTHTTATMKMT2AMEN1
SCHEMBL12793192 0.79 ALDH1A1 (0.42) MAPTHTTATMPIK3CDPIK3CA
SCHEMBL30979847 0.79 ALDH1A1 (0.42) MAPTHTTATMPIK3CDPIK3CA
SCHEMBL17051465 0.78 HSD17B10 (0.48) MAPTHTTATMPIK3CDPIK3CA
SCHEMBL9535679 0.77 GPR3 (0.58) MAPTHTTATMCA12BRD4
SCHEMBL30772924 0.77 GPR3 (0.58) MAPTHTTATMCA12BRD4
SCHEMBL543765 0.77 ATM (0.47) HTTATMCA12BRD4BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10211409-B2 Noncrystallizable sensitized layers for OLED and OEDs MOLECULAR GLASSES, INC. (US) 2019-02-19 US disclosed
US-20040132228-A1 Method and system for fabricating an OLED HONEYWELL INTERNATIONAL INC. (US) 2004-07-08 US disclosed
EP-1401035-A2 Novel light emitting layers for LED devices based on high Tg Polymer matrix compositions AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-03-24 EP disclosed