Carbamic Acid

Carbamic Acid

SCHEMBL6537377

CO[Si](CCCN(C)C(=O)O)(OC)OC.NC(=O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL512341 0.94 BCHE (0.32) BCHEACHE
SCHEMBL3841863 0.89 BCHE (0.34) BCHEACHE
SCHEMBL5916792 0.87 BCHE (0.36) BCHEACHE
SCHEMBL5916727 0.87 BCHE (0.36) BCHEACHE
SCHEMBL5916599 0.83
SCHEMBL4396822 0.83
SCHEMBL5916649 0.83 ALDH1A1 (0.31)
SCHEMBL28768318 0.82 NOS3 (0.30) NOS3NOS1NOS2
SCHEMBL5916511 0.81
SCHEMBL6943127 0.79 LMNA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6673954-B1 REACTING AN AMINOORGANOSILANE WITH AN ORGANOCARBONATE ESTER, BASIC CATALYST GENERAL ELECTRIC COMPANY 2004-01-06 US disclosed