Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6537451 | 0.85 | CRBN (0.72) | CRBNMAPTALDH1A1OR51E2FKBP5 | |
| Sulfuric Acid SCHEMBL5145399 | 0.85 | CRBN (0.72) | CRBNMAPTALDH1A1OR51E2FKBP5 | |
| SCHEMBL217901 | 0.81 | CRBN (0.65) | CRBNMAPTALDH1A1OR51E2FKBP5 | |
| 2-Pyrrolidone SCHEMBL27698785 | 0.78 | OR51E2 (0.62) | CRBNOR51E2FKBP5 | |
| SCHEMBL5778743 | 0.77 | CRBN (1.00) | CRBNMAPTALDH1A1OR51E2FKBP5 | |
| SCHEMBL26618 | 0.77 | — | — | |
| Caprolactam SCHEMBL28069032 | 0.75 | CRBN (0.61) | CRBNOR51E2FKBP5 | |
| Succinimide SCHEMBL27863987 | 0.75 | CRBN (0.69) | CRBN | |
| Succinimide SCHEMBL30302994 | 0.75 | CRBN (0.69) | CRBN | |
| Methyl Alcohol SCHEMBL28109851 | 0.75 | CRBN (0.81) | CRBNMAPTALDH1A1OR51E2FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040249159-A1 | Novel piperidin-2,6-dione disulphate salts and their use for the treatment of stress related affective disorders | BAUSCH & LOMB INCORPORATED | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249159-A1 | Novel piperidin-2,6-dione disulphate salts and their use for the treatment of stress related affective disorders | EGLN2, EGLN3, HTR2C | CRBN 3425/4885MAPT 3549/4885ALDH1A1 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.