Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537536 | 0.88 | KDR (0.52) | KDRMEN1KMT2AHPGDMAPT | |
| SCHEMBL6537986 | 0.87 | KDR (0.50) | KDRMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6537757 | 0.86 | KDR (0.58) | KDRMEN1KMT2AHPGDMAPT | |
| SCHEMBL6537944 | 0.85 | RAB9A (0.56) | KDRMEN1KMT2AMAPTPLEC | |
| SCHEMBL6537959 | 0.85 | RAB9A (0.56) | KDRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6537751 | 0.82 | RAB9A (0.69) | MEN1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL6537870 | 0.82 | SMN1; SMN2 (0.52) | KDRMAPTL3MBTL1PTGESKDM4E | |
| SCHEMBL6537919 | 0.82 | CYP1A2 (0.55) | MEN1KMT2ACYP1A2HPGDCYP2C19 | |
| SCHEMBL6538190 | 0.81 | KDR (0.67) | KDRMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL29510019 | 0.81 | KDR (1.00) | KDRMEN1KMT2ACYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |