Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537606 | 0.86 | KDR (0.67) | KDRL3MBTL1SMN1; SMN2HPGDMAPT | |
| SCHEMBL27782344 | 0.85 | KDR (0.78) | KDRL3MBTL1SMN1; SMN2HPGDHTT | |
| SCHEMBL6537959 | 0.81 | RAB9A (0.56) | KDRL3MBTL1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6537944 | 0.81 | RAB9A (0.56) | KDRL3MBTL1SMN1; SMN2MAPTPLEC | |
| SCHEMBL6537536 | 0.81 | KDR (0.52) | KDRL3MBTL1SMN1; SMN2HPGDHTT | |
| SCHEMBL6537986 | 0.80 | KDR (0.50) | KDRL3MBTL1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6538190 | 0.80 | KDR (0.67) | KDRL3MBTL1HTTMAPTMEN1 | |
| SCHEMBL6537334 | 0.79 | L3MBTL1 (0.70) | KDRL3MBTL1HTTMAPTMEN1 | |
| SCHEMBL6537751 | 0.78 | RAB9A (0.69) | SMN1; SMN2HPGDMAPTMEN1KMT2A | |
| SCHEMBL6537870 | 0.78 | SMN1; SMN2 (0.52) | KDRL3MBTL1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |