Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537755 | 0.83 | CHUK (0.48) | CCR8KMT2AALDH1A1P2RX7VCAM1 | |
| SCHEMBL6537634 | 0.81 | GRIN2D (0.49) | CCR8KMT2AALDH1A1TDP1P2RX7 | |
| SCHEMBL6537690 | 0.81 | ALDH1A1 (0.51) | CCR8KMT2AALDH1A1TDP1HSD17B10 | |
| SCHEMBL1423220 | 0.80 | TDP1 (0.43) | KMT2AALDH1A1ATMTDP1TYMS | |
| SCHEMBL2720890 | 0.78 | CCR8 (0.40) | CCR8KMT2AALDH1A1ATMTDP1 | |
| SCHEMBL31399705 | 0.76 | ALDH1A1 (0.59) | ALDH1A1ATMTDP1TYMSHSD17B10 | |
| SCHEMBL6537493 | 0.76 | ALDH1A1 (0.58) | CCR8KMT2AALDH1A1TDP1HSD17B10 | |
| SCHEMBL22492408 | 0.73 | CCR8 (0.48) | CCR8KMT2AALDH1A1P2RX7HSD17B10 | |
| SCHEMBL20915014 | 0.72 | ALDH1A1 (0.42) | ALDH1A1ATMTDP1TYMSVCAM1 | |
| SCHEMBL22532255 | 0.70 | CASP6 (0.50) | KMT2AALDH1A1ATMTDP1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |