Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.53 |
| ▸ | AHCY | P23526 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365540 | 0.91 | PRMT5 (0.58) | PRMT5WDR77AHCYADORA3DPP4 | |
| SCHEMBL28672423 | 0.88 | PRMT5 (0.53) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL2120934 | 0.86 | PRMT5 (0.67) | PRMT5WDR77AHCYADORA3DPP4 | |
| SCHEMBL11681025 | 0.85 | PRMT5 (0.51) | PRMT5WDR77AHCYADORA3DPP4 | |
| SCHEMBL3515656 | 0.85 | PRMT5 (0.50) | PRMT5WDR77AHCYADORA3DPP4 | |
| SCHEMBL28985735 | 0.84 | PRMT5 (0.50) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL3515650 | 0.84 | PRMT5 (0.50) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL5498775 | 0.84 | AHCY (0.51) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL9155536 | 0.84 | AHCY (0.51) | PRMT5WDR77AHCYADORA3ADORA2A | |
| SCHEMBL9052971 | 0.83 | AHCY (0.49) | PRMT5WDR77AHCYADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485395-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | Biota, Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003072757-A9 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA INC (US) | 2004-10-21 | — | — | WO | claimed |
| WO-2003072757-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA, INC. (US) | 2003-09-04 | — | — | WO | claimed |
| WO-2003072757-A9 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA INC (US) | 2004-10-21 | — | — | WO | disclosed |
| CN-1109755-A | Antiviral, Highly water soluble, stable, crystalline salts of 2',3'-dideoxyinosine monohydrate 2',3',-dideoxy-2',3'-didehydrothymidine monohydrate and 2',3'-dideoxy-2'-fluoroinosine hemihydrate | BRISTOL MYERS SQUIBB CO (US) | 1995-10-11 | — | — | CN | disclosed |
| CN-1027896-C | Preparation method of inosine and thymidine derivative salt with antiviral effect | BRISTOL MYERS SQUIBB CO (US) | 1995-03-15 | — | — | CN | disclosed |
| CN-1047676-A | Preparation method of inosine and thymidine derivative salt with antiviral effect | BRISTOL MYERS SQUIBB CO (US) | 1990-12-12 | — | — | CN | disclosed |