Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538568 | 1.00 | PYGL (0.63) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL1814865 | 0.83 | PYGL (0.61) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL8332561 | 0.83 | PYGL (0.61) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL9239176 | 0.79 | PYGL (0.63) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL8619293 | 0.79 | PYGL (0.63) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL27498579 | 0.79 | PYGL (0.56) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL7033031 | 0.75 | PYGL (0.55) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL8152014 | 0.75 | PYGL (0.55) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL6401981 | 0.74 | PYGL (0.51) | PYGLKDM4EGMNNLMNAMAPT | |
| SCHEMBL6489385 | 0.73 | PYGL (0.50) | PYGLKDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485395-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | Biota, Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003072757-A9 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA INC (US) | 2004-10-21 | — | — | WO | claimed |
| WO-2003072757-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA, INC. (US) | 2003-09-04 | — | — | WO | claimed |
| WO-2003072757-A9 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA INC (US) | 2004-10-21 | — | — | WO | disclosed |