SCHEMBL1814865

SCHEMBL1814865

Nc1cnc(C2O[C@H](CO)[C@@H](O)[C@H]2O)[nH]1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PYGL P06737 9/20 0.61
HIF1A Q16665 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GMNN O75496 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48
STAT6 P42226 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332561 1.00 PYGL (0.61) PYGLHIF1AKDM4EGMNNLMNA
SCHEMBL6538568 0.83 PYGL (0.63) PYGLHIF1AKDM4EGMNNLMNA
SCHEMBL6538415 0.83 PYGL (0.63) PYGLHIF1AKDM4EGMNNLMNA
SCHEMBL27498579 0.80 PYGL (0.56) PYGLHIF1AKDM4EGMNNLMNA
SCHEMBL5310180 0.80 ADORA1 (0.46) PYGL
SCHEMBL3810104 0.80 PYGL (0.39) PYGL
SCHEMBL187957 0.79 FBP1 (0.50) SMN1; SMN2
SCHEMBL8619293 0.77 PYGL (0.63) PYGLHIF1AKDM4EGMNNLMNA
SCHEMBL9239176 0.77 PYGL (0.63) PYGLHIF1AKDM4EGMNNLMNA
SCHEMBL8152014 0.74 PYGL (0.55) PYGLHIF1AKDM4EGMNNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618084-B2 Method for producing transformant TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2026-05-05 US disclosed
US-12338454-B2 Helper plasmid for transformation, method for producing transformant using the same, and transformation method TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2025-06-24 US disclosed
US-20240043855-A1 A HELPER PLASMID FOR TRANSFORMATION, A METHOD FOR PRODUCING A TRANSFORMANT USING THE SAME, AND A METHOD OF TRANSFORMATION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2024-02-08 US disclosed
US-20240043875-A1 A PLASMID FOR TRANSFORMATION, A METHOD FOR PRODUCING A TRANSFORMANT USING THE SAME AND A METHOD OF TRANSFORMATION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2024-02-08 US disclosed
US-20240002885-A1 PLASMID FOR TRANSFORMATION, METHOD FOR PRODUCING TRANSFORMANT USING THE SAME, AND TRANSFORMATION METHOD TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2024-01-04 US disclosed
CN-110494131-B Application of spermine and derivatives thereof in preparation of antitumor drugs 广州君赫生物科技有限公司 2022-11-08 CN disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
WO-2022138647-A1 A HELPER PLASMID FOR TRANSFORMATION, A METHOD FOR PRODUCING A TRANSFORMANT USING THE SAME, AND A METHOD OF TRANSFORMATION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-06-30 WO disclosed
WO-2022138649-A1 A PLASMID FOR TRANSFORMATION, A METHOD FOR PRODUCING A TRANSFORMANT USING THE SAME, AND A METHOD OF TRANSFORMATION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-06-30 WO disclosed
WO-2022118866-A1 PLASMID FOR TRANSFORMATION, METHOD FOR PRODUCING TRANSFORMANT USING THE SAME, AND TRANSFORMATION METHOD TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-06-09 WO disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed
US-20140248689-A1 GLUCOSE-INDUCED INACTIVATION/DEGRADATION-RESISTANT TRANSPORTER GENE AND USE THEREOF SUNTORY HOLDINGS LIMITED (JP) 2014-09-04 US disclosed
US-8735092-B2 Glucose-induced inactivation/degradation-resistant transporter gene and use thereof SUNTORY HOLDINGS LIMITED (JP) 2014-05-27 US disclosed
EP-2202300-B1 GLUCOSE-INDUCED INACTIVATION/DEGRADATION RESISTANT TRANSPORTER GENE AND USE THEREOF SUNTORY HOLDINGS LTD (JP) 2014-05-14 EP disclosed
US-20110104331-A1 GLUCOSE-INDUCED INACTIVATION/DEGRADATION-RESISTANT TRANSPORTER GENE AND USE THEREOF SUNTORY HOLDINGS LIMITED (JP) 2011-05-05 US disclosed
EP-2202300-A1 GLUCOSE-INDUCED INACTIVATION/DEGRADATION RESISTANT TRANSPORTER GENE AND USE THEREOF Suntory Holdings Limited (JP) 2010-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618084-B2 Method for producing transformant SRRT, RAD52, FEN1 PYGL 1668/4885HIF1A 3409/4885KDM4E 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.