Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539007 | 0.91 | PDE9A (0.39) | PDE9ACYP1A2CYP3A4CLK4CYP2D6 | |
| SCHEMBL6538385 | 0.90 | RET (0.41) | PDE9ACYP1A2CYP3A4CLK4CYP2D6 | |
| SCHEMBL6539255 | 0.83 | KDM4E (0.41) | ALDH1A1HSD17B10ALOX15USP2KMT2A | |
| SCHEMBL6538445 | 0.81 | CSNK1D (0.47) | ALDH1A1HSD17B10CYP2C19RAB9APOLB | |
| SCHEMBL6134404 | 0.79 | ADORA2A (0.45) | GPR84PDE9ACYP1A2CYP3A4CLK4 | |
| SCHEMBL6538914 | 0.79 | TP53 (0.38) | HSD17B10POLBKDM4E | |
| SCHEMBL6539021 | 0.76 | TP53 (0.45) | CYP3A4CLK4ALDH1A1POLBKDM4E | |
| SCHEMBL6133144 | 0.75 | RAB9A (0.48) | ALDH1A1USP2MAPK1KMT2ARAB9A | |
| SCHEMBL6538384 | 0.75 | TP53 (0.44) | KMT2ARAB9APOLBKDM4E | |
| SCHEMBL6539065 | 0.74 | ADORA1 (0.43) | CYP1A2CYP3A4CYP2C19RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | ADORA1, ADORA2A, P2RX5 | GPR84 2284/4885PDE9A 282/4885CYP1A2 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.