Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7316392 | 0.93 | TP53 (0.47) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6538606 | 0.92 | TP53 (0.47) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7323795 | 0.92 | CA12 (0.56) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6539243 | 0.92 | TP53 (0.56) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7318099 | 0.86 | F2RL3 (0.41) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL6539767 | 0.85 | MAPT (0.57) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7325659 | 0.84 | SIRT2 (0.46) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7323575 | 0.84 | CA12 (0.46) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7323148 | 0.84 | LMNA (0.48) | MAPTTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7324043 | 0.84 | MTOR (0.42) | MAPTTP53CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743776-B2 | ANTIFUNGAL, BETA-1,3-GLUCAN SYNTHASE INHIBITOR, PNEUMOCYSTIS CARINII; AMIDATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |