Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7323795

CCOC(=O)c1ccc(-c2cn3nc(-c4ccc(OC)cc4)sc3n2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA9 Q16790 3/20 0.56
F2RL3 Q96RI0 4/20 0.49
TP53 P04637 3/20 0.46
POLB P06746 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
MAPT P10636 7/20 0.45
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
RARA P10276 1/20 0.43
RARB P10826 1/20 0.43
RARG P13631 1/20 0.43
HIF1A Q16665 1/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6538546 0.92 MAPT (0.53) CA12CA1CA2CA9F2RL3
Trifluoroacetic Acid SCHEMBL6539243 0.91 TP53 (0.56) CA12CA1CA2CA9F2RL3
Trifluoroacetic Acid SCHEMBL7316392 0.90 TP53 (0.47) CA12CA1CA2CA9F2RL3
Trifluoroacetic Acid SCHEMBL6538606 0.89 TP53 (0.47) CA12CA1CA2CA9F2RL3
Trifluoroacetic Acid SCHEMBL7318099 0.86 F2RL3 (0.41) CA12CA1CA2CA9F2RL3
Trifluoroacetic Acid SCHEMBL7325659 0.85 SIRT2 (0.46) CA12CA1CA2CA9TP53
Trifluoroacetic Acid SCHEMBL7323148 0.84 LMNA (0.48) CA12CA1CA2CA9TP53
Trifluoroacetic Acid SCHEMBL7324043 0.84 MTOR (0.42) CA12CA1CA2CA9TP53
Trifluoroacetic Acid SCHEMBL7317609 0.84 TP53 (0.41) CA12CA1CA2CA9TP53
SCHEMBL7317639 0.83 CA12 (0.51) CA12CA1CA2CA9F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232290-B1 FUNGICIDES AGAINST PNEUMOCYSTIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-15 US disclosed