Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539488 | 0.92 | ADRB3 (0.57) | ADRB3ADRB1MEN1KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6538740 | 0.89 | ADRB3 (0.68) | ADRB3ADRB1CA12CA1CA2 | |
| SCHEMBL6539241 | 0.87 | ADRB3 (0.60) | ADRB3ADRB1CA12CA1CA2 | |
| SCHEMBL6539720 | 0.87 | ADRB3 (0.60) | ADRB3ADRB1KDM4EMEN1PKM | |
| SCHEMBL6539718 | 0.85 | ADRB3 (0.61) | ADRB3ADRB1SMN1; SMN2HPGD | |
| SCHEMBL6538790 | 0.85 | ADRB3 (0.56) | ADRB3ADRB1KDM4EMEN1KMT2A | |
| SCHEMBL7532289 | 0.83 | ADRB3 (0.58) | ADRB3ADRB1 | |
| SCHEMBL6541344 | 0.83 | ADRB3 (0.58) | ADRB3ADRB1MEN1KMT2A | |
| SCHEMBL6539506 | 0.82 | ADRB3 (0.59) | ADRB3ADRB1 | |
| SCHEMBL7533764 | 0.82 | ADRB3 (0.58) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |