Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538746 | 1.00 | PPARA (0.46) | PPARAPPARGCCR2CACNA1BAPBA1 | |
| SCHEMBL17135524 | 0.80 | NPC1 (0.47) | CCR2NPC1RAB9A | |
| SCHEMBL17135523 | 0.80 | NPC1 (0.47) | CCR2NPC1RAB9A | |
| SCHEMBL6541442 | 0.80 | CAPN1 (0.38) | PPARGKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL6541438 | 0.80 | CAPN1 (0.38) | PPARGKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL6541124 | 0.79 | NAMPT (0.42) | ALDH1A1 | |
| SCHEMBL6541226 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL6541119 | 0.79 | NAMPT (0.42) | ALDH1A1 | |
| SCHEMBL6539545 | 0.75 | CACNA1G (0.43) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL6186251 | 0.74 | KCNH2 (0.42) | MEN1KMT2AALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |