Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.35 |
| ▸ | ABL1 | P00519 | 7/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.35 |
| ▸ | PRKDC | P78527 | 5/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | HCK | P08631 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 3/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538756 | 0.89 | POLB (0.37) | SRCPIK3CDABL1PIK3CAPIK3CB | |
| SCHEMBL6538477 | 0.86 | ADORA2A (0.38) | SRCPIK3CDABL1PIK3CAPIK3CB | |
| SCHEMBL6538765 | 0.80 | MET (0.40) | RETPDE1APDE1BPDE1CPOLB | |
| SCHEMBL6539038 | 0.79 | ADORA2A (0.36) | SRCPIK3CDABL1PIK3CAPIK3CB | |
| SCHEMBL6538926 | 0.79 | POLB (0.39) | SRCPIK3CDABL1PIK3CAPIK3CB | |
| SCHEMBL6539119 | 0.79 | ADORA2A (0.36) | SRCPIK3CDABL1PIK3CAPIK3CB | |
| SCHEMBL6538453 | 0.78 | RXFP1 (0.38) | — | |
| SCHEMBL6538806 | 0.78 | PDE1A (0.42) | RETPDE1APDE1BPDE1CEGFR | |
| SCHEMBL6538474 | 0.77 | RET (0.41) | SRCPIK3CDABL1PIK3CAPIK3CB | |
| SCHEMBL6538517 | 0.77 | AKT1 (0.39) | SRCPIK3CDABL1PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | ADORA1, ADORA2A, P2RX5 | SRC 3470/4885PIK3CD 809/4885ABL1 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.