Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HEXA | P06865 | 2/20 | 0.45 |
| ▸ | HEXB | P07686 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538960 | 0.87 | RAB9A (0.65) | RAB9AHPGDHSD17B10TDP1NPSR1 | |
| SCHEMBL6539359 | 0.84 | RAB9A (0.61) | RAB9AHPGDHSD17B10TDP1NPSR1 | |
| SCHEMBL6229214 | 0.83 | RAB9A (0.60) | RAB9AHPGDHSD17B10TDP1NPSR1 | |
| SCHEMBL6539666 | 0.83 | RAB9A (0.58) | RAB9AHPGDHSD17B10TDP1NPSR1 | |
| SCHEMBL6269691 | 0.80 | PPARD (0.41) | HPGDPOLBMAPTKMT2AMEN1 | |
| SCHEMBL6278582 | 0.79 | HSD17B10 (0.43) | RAB9AHPGDHSD17B10POLBNPC1 | |
| SCHEMBL6539369 | 0.78 | ALDH1A1 (0.42) | RAB9AHPGDHSD17B10TDP1NPSR1 | |
| Hydrochloric Acid SCHEMBL6539296 | 0.78 | HSD17B10 (0.42) | RAB9AHPGDHSD17B10POLBNPC1 | |
| SCHEMBL6539583 | 0.77 | NPSR1 (0.51) | RAB9AHPGDHSD17B10TDP1NPSR1 | |
| SCHEMBL6275665 | 0.76 | PPARD (0.38) | RAB9AHPGDHSD17B10POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | RAB9A 4006/4885HPGD 29/4885HSD17B10 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.