Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539645 | 1.00 | MAPT (0.38) | MAPTALDH1A1HSD17B10CYP3A4EPHX1 | |
| SCHEMBL6541442 | 0.88 | CAPN1 (0.38) | MAPTALDH1A1HSD17B10CYP3A4HPGD | |
| SCHEMBL6541438 | 0.88 | CAPN1 (0.38) | MAPTALDH1A1HSD17B10CYP3A4HPGD | |
| SCHEMBL17103824 | 0.87 | PPARA (0.34) | EPHX1PPARGPPID | |
| SCHEMBL17103825 | 0.87 | PPARA (0.34) | EPHX1PPARGPPID | |
| SCHEMBL6539545 | 0.83 | CACNA1G (0.43) | MAPTALDH1A1HSD17B10CYP3A4EPHX1 | |
| SCHEMBL6539531 | 0.83 | CACNA1G (0.43) | MAPTALDH1A1HSD17B10CYP3A4EPHX1 | |
| SCHEMBL6541230 | 0.82 | ALDH1A1 (0.39) | MAPTALDH1A1HSD17B10CYP3A4HPGD | |
| SCHEMBL6541124 | 0.82 | NAMPT (0.42) | ALDH1A1HSD17B10ABCB1 | |
| SCHEMBL6541226 | 0.82 | ALDH1A1 (0.39) | MAPTALDH1A1HSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |