Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539766 | 0.87 | IKBKB (0.46) | ALDH1A1IKBKBPPARDKMT2AKDM4E | |
| SCHEMBL6539373 | 0.86 | PPARD (0.43) | ALDH1A1IKBKBPPARDKDM4EMEN1 | |
| SCHEMBL6539903 | 0.85 | PPARD (0.41) | MTNR1AMTNR1BALDH1A1IKBKBLMNA | |
| SCHEMBL6539080 | 0.84 | IKBKB (0.51) | ALDH1A1IKBKBSMN1; SMN2LMNAPPARD | |
| SCHEMBL6540529 | 0.83 | MTNR1A (0.58) | MTNR1AMTNR1BUSP2ALOX15TSHR | |
| SCHEMBL6540499 | 0.82 | MTNR1A (0.57) | MTNR1AMTNR1BUSP2ALOX15TSHR | |
| SCHEMBL6272841 | 0.81 | PPARD (0.43) | MTNR1AMTNR1BALDH1A1NPC1LMNA | |
| SCHEMBL6252437 | 0.81 | MTNR1A (0.42) | MTNR1AMTNR1BMAPK1ALDH1A1IKBKB | |
| SCHEMBL6539856 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1IKBKBNPC1 | |
| SCHEMBL6538996 | 0.80 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1IKBKBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | MTNR1A 410/4885MTNR1B 474/4885USP2 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.