Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539373 | 0.92 | PPARD (0.43) | IKBKBPPARDKDM4EALDH1A1PTGS2 | |
| SCHEMBL6539080 | 0.90 | IKBKB (0.51) | IKBKBPPARDKDM4EALDH1A1NR4A2 | |
| SCHEMBL6539903 | 0.89 | PPARD (0.41) | IKBKBPPARDKDM4EALDH1A1PTGS2 | |
| SCHEMBL6539668 | 0.87 | MTNR1A (0.58) | IKBKBPPARDKDM4EALDH1A1MEN1 | |
| SCHEMBL6235166 | 0.86 | PPARD (0.42) | IKBKBPPARDKDM4EALDH1A1PTGS2 | |
| SCHEMBL6284293 | 0.86 | PPARD (0.42) | IKBKBPPARDKDM4EALDH1A1PTGS2 | |
| SCHEMBL6538618 | 0.85 | PPARD (0.42) | IKBKBPPARDKDM4EALDH1A1NR4A2 | |
| SCHEMBL6231751 | 0.85 | IKBKB (0.47) | IKBKBPPARDKDM4EALDH1A1NR4A2 | |
| SCHEMBL6208406 | 0.84 | PPARD (0.41) | PPARDKDM4EALDH1A1PTGS2NR4A2 | |
| SCHEMBL6539837 | 0.84 | HPGD (0.42) | PPARDKDM4EALDH1A1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | IKBKB 170/4885PPARD 1747/4885KDM4E 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.