Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539479 | 0.94 | KCNH2 (0.39) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL2086387 | 0.86 | TSHR (0.42) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL7104710 | 0.80 | KCNH2 (0.41) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL6539573 | 0.80 | L3MBTL1 (0.41) | KMT2AALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL23381218 | 0.78 | KCNH2 (0.43) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL18403079 | 0.78 | KCNH2 (0.43) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL19505906 | 0.78 | KCNH2 (0.43) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL9740019 | 0.78 | KCNH2 (0.43) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL24901344 | 0.78 | KCNH2 (0.40) | KCNH2KCNA5LMNASMN1; SMN2KMT2A | |
| SCHEMBL19865652 | 0.78 | KCNH2 (0.43) | KCNH2KCNA5LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082757-A1 | Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs | ASTELLAS PHARMA INC. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1366065-A1 | ECHINOCANDIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE THEREOF AS DRUGS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002068456-A1 | ECHINOCANDIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE THEREOF AS DRUGS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-06 | — | — | WO | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082757-A1 | Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs | MAN2B1, MAN2A1, ALG1 | KCNH2 3621/4885KCNA5 3173/4885LMNA 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.