Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539148 | 0.85 | HPGD (0.51) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL6539527 | 0.81 | TP53 (0.39) | KDM4EALDH1A1LMNAHSD11B1HSD17B10 | |
| SCHEMBL6539032 | 0.80 | TP53 (0.38) | KDM4EMEN1KMT2ALMNATP53 | |
| SCHEMBL6539233 | 0.78 | GABRA1 (0.40) | HPGDKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL6538758 | 0.78 | PDE10A (0.38) | KDM4EALDH1A1HSD11B1TP53POLB | |
| SCHEMBL6538517 | 0.77 | AKT1 (0.39) | KDM4EALDH1A1GAALMNARXFP1 | |
| SCHEMBL6537897 | 0.77 | NPSR1 (0.47) | HPGDKDM4EALDH1A1GALR3GAA | |
| SCHEMBL6538844 | 0.76 | TP53 (0.37) | ALDH1A1LMNAKDM5AKDM6BKDM5C | |
| SCHEMBL6538925 | 0.76 | AKT1 (0.42) | KDM4EALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL12427051 | 0.75 | HPGD (0.69) | HPGDKDM4EALDH1A1GALR3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067955-A1 | Pyridazinone compound and pharmaceutical use thereof | ADORA1, ADORA2A, P2RX5 | HPGD 322/4885KDM4E 3052/4885ALDH1A1 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.