Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538691 | 0.84 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6539439 | 0.82 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL136284 | 0.80 | CA1 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10728975 | 0.80 | MEN1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL403210 | 0.80 | CA12 (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9335427 | 0.79 | TSHR (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23419469 | 0.78 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14527079 | 0.77 | ALDH1A1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20876261 | 0.77 | TSHR (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6539001 | 0.77 | HPGD (0.53) | HPGDLMNAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545024-B1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-SUBSTITUTED PHENYL)-3-PHENYLPROPYLAMINES, INTERMEDIATES FOR MAKING HYDROXYTOLTERODINE AND FESOTERODINE | LEK PHARMACEUTICALS (SI) | 2016-08-03 | — | — | EP | disclosed |
| US-20130197082-A1 | SHORT SYNTHESIS OF TOLTERODINE, INTERMEDIATES AND METABOLITES | LEK PHARMACEUTICALS D.D. (SI) | 2013-08-01 | — | — | US | disclosed |
| US-20090062385-A1 | DEUTERIUM-ENRICHED FESOTERODINE | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090062385-A1 | DEUTERIUM-ENRICHED FESOTERODINE | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-6809225-B2 | BY HYDROCARBONYLATION/HYDROFORMYLATION WITH SUBSEQUENT REDUCTIVE AMINATION | SCHWARZ PHARMA AG (DE) | 2004-10-26 | — | — | US | disclosed |
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | UCB PHARMA GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197082-A1 | SHORT SYNTHESIS OF TOLTERODINE, INTERMEDIATES AND METABOLITES | COMT, UGT1A7, PAH | CA12 4629/4885CA1 4239/4885CA2 3807/4885 |
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | HNMT, CYP1A1, HRH3 | CA12 2817/4885CA1 2036/4885CA2 2141/4885 |
| US-20090062385-A1 | DEUTERIUM-ENRICHED FESOTERODINE | AVPR2, SSTR3, SLC6A3 | CA12 2203/4885CA1 3167/4885CA2 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.