Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539783 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| SCHEMBL6539669 | 0.89 | KDM4E (0.41) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| Hydrochloric Acid SCHEMBL6207772 | 0.88 | KMT2A (0.39) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| Hydrochloric Acid SCHEMBL6539698 | 0.88 | KMT2A (0.39) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| SCHEMBL6539388 | 0.88 | PPARD (0.38) | PPARDKMT2AMEN1 | |
| SCHEMBL6258696 | 0.84 | PPARD (0.40) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| SCHEMBL6255182 | 0.83 | PPARD (0.37) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| SCHEMBL6231402 | 0.82 | MTNR1A (0.45) | ALDH1A1KDM4EHPGDPPARDKMT2A | |
| SCHEMBL6540424 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| SCHEMBL6538937 | 0.81 | NPSR1 (0.51) | ALDH1A1MAPTKDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | ALDH1A1 163/4885MAPT 4796/4885KDM4E 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.