SCHEMBL6540100

SCHEMBL6540100

COc1ccc(Sc2ccc(CCN(Cc3ccccc3)C(=O)O)cc2)cc1OC

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
LPAR1 Q92633 5/20 0.48
ACHE P22303 4/20 0.48
BCHE P06276 3/20 0.48
LPAR5 Q9H1C0 3/20 0.47
LPAR2 Q9HBW0 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
PLAAT3 P53816 1/20 0.45
PLAAT5 Q96KN8 1/20 0.45
PLAAT2 Q9NWW9 1/20 0.45
PLAAT4 Q9UL19 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6540059 0.86 L3MBTL1 (0.49) L3MBTL1KMT2AMEN1LPAR1LPAR5
SCHEMBL6552605 0.85 LPAR1 (0.62) L3MBTL1KMT2AMEN1LPAR1ACHE
SCHEMBL6539665 0.85 LPAR1 (0.57) L3MBTL1KMT2AMEN1LPAR1LPAR5
SCHEMBL6540146 0.81 LPAR1 (0.52) L3MBTL1KMT2AMEN1LPAR1ACHE
SCHEMBL6541428 0.81 L3MBTL1 (0.58) L3MBTL1LPAR1GAA
SCHEMBL6540922 0.80 L3MBTL1 (0.48) L3MBTL1KMT2AMEN1LPAR1BCHE
SCHEMBL6540825 0.80 OPRK1 (0.50) L3MBTL1KMT2AMEN1LPAR1LPAR5
SCHEMBL7228409 0.75 MEN1 (0.61) L3MBTL1KMT2AMEN1
SCHEMBL6540023 0.74 L3MBTL1 (0.51) L3MBTL1KMT2AMEN1LPAR1LPAR5
SCHEMBL6541405 0.74 LPAR1 (0.54) L3MBTL1KMT2AMEN1LPAR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040138462-A1 Aminoalcohol derivatives ASTELLAS PHARMA INC. (JP) 2004-07-15 US disclosed
EP-1389185-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-02-18 EP disclosed
WO-2002094770-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040138462-A1 Aminoalcohol derivatives BPHL, FANCD2, HRH2 L3MBTL1 2987/4885KMT2A 432/4885MEN1 4140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.