Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.49 |
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540559 | 0.85 | LPAR1 (0.56) | TAS2R14LPAR1CA12CA1CA2 | |
| SCHEMBL6540099 | 0.85 | HTR6 (0.55) | L3MBTL1TAS2R14ALDH1A1GAALPAR1 | |
| SCHEMBL6540116 | 0.82 | TAS2R14 (0.52) | TAS2R14ALDH1A1TP53TSHRLPAR1 | |
| SCHEMBL6274189 | 0.81 | MEN1 (0.48) | MAPK1CA12CA1CA2CA4 | |
| SCHEMBL6540100 | 0.81 | L3MBTL1 (0.59) | L3MBTL1GAALPAR1 | |
| SCHEMBL6798502 | 0.80 | CA12 (0.55) | L3MBTL1TAS2R14CA12CA1CA2 | |
| SCHEMBL6541013 | 0.80 | CA12 (0.50) | CA12CA1CA2CA4 | |
| SCHEMBL6554335 | 0.78 | L3MBTL1 (0.46) | L3MBTL1TAS2R14ALDH1A1GAATP53 | |
| SCHEMBL7419350 | 0.77 | PDE4D (0.67) | L3MBTL1TAS2R14ALDH1A1GAATP53 | |
| SCHEMBL6540945 | 0.77 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1GAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | L3MBTL1 2987/4885TAS2R14 3056/4885ALDH1A1 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.