Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 8/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 8/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 8/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540818 | 0.83 | MEN1 (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL6540139 | 0.80 | HSD11B1 (0.50) | CNR2MMP1MMP9MMP13 | |
| SCHEMBL6540252 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL6330677 | 0.79 | CYP3A4 (0.64) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6541332 | 0.78 | CXCR2 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL6331086 | 0.78 | KMT2A (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL6540200 | 0.76 | KMT2A (0.46) | CYP3A4CYP2C9CA1CA2CA7 | |
| SCHEMBL6539832 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KMT2AACACBMMP1MMP9 | |
| SCHEMBL6540374 | 0.76 | AKR1C3 (0.42) | CYP3A4CYP2C19MEN1TSHRKMT2A | |
| SCHEMBL6336665 | 0.74 | GSK3B (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ALDH1A1 188/4885CYP3A4 4197/4885CYP2C9 3959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.