Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.42 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 6/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 6/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540818 | 0.81 | MEN1 (0.46) | KMT2AABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6540519 | 0.80 | MAPK1 (0.47) | AKR1C3KMT2AMAPK1TDP1CYP2C19 | |
| SCHEMBL6540097 | 0.79 | CYP2C9 (0.40) | CYP2C19CYP1A2CYP3A4POLB | |
| SCHEMBL6541332 | 0.78 | CXCR2 (0.39) | KMT2AABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6540139 | 0.78 | HSD11B1 (0.50) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6539832 | 0.76 | ALDH1A1 (0.57) | KMT2A | |
| SCHEMBL6540200 | 0.76 | KMT2A (0.46) | KMT2AMEN1CYP1A2CYP3A4POLB | |
| SCHEMBL6540103 | 0.76 | ALDH1A1 (0.41) | KMT2ACYP2C19MEN1CYP3A4TSHR | |
| SCHEMBL6330677 | 0.75 | CYP3A4 (0.64) | MAPK1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5581691 | 0.74 | MAPT (0.60) | AKR1C3CYP2C19TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | AKR1C3 246/4885SFRP1 4764/4885KMT2A 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.