Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999535 | 1.00 | NR5A1 (0.42) | NR5A1L3MBTL1TDP1PLA2G4BMEN1 | |
| SCHEMBL7003091 | 0.98 | NR5A1 (0.39) | NR5A1L3MBTL1TDP1PLA2G4BMEN1 | |
| SCHEMBL9687974 | 0.96 | MEN1 (0.44) | NR5A1L3MBTL1TDP1PLA2G4BMEN1 | |
| SCHEMBL9688098 | 0.95 | MEN1 (0.41) | NR5A1L3MBTL1TDP1PLA2G4BMEN1 | |
| SCHEMBL990609 | 0.92 | L3MBTL1 (0.39) | NR5A1L3MBTL1TDP1PLA2G4BALDH1A1 | |
| SCHEMBL7299873 | 0.89 | TSHR (0.40) | NR5A1L3MBTL1TDP1MEN1THRB | |
| SCHEMBL5958235 | 0.84 | TSHR (0.36) | L3MBTL1TDP1KDM4ELTA4H | |
| SCHEMBL991496 | 0.84 | MEN1 (0.42) | NR5A1MEN1THRBHTTKMT2A | |
| SCHEMBL16892528 | 0.84 | ALDH1A1 (0.49) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL16892524 | 0.84 | ALDH1A1 (0.45) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082757-A1 | Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs | ASTELLAS PHARMA INC. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1366065-A1 | ECHINOCANDIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE THEREOF AS DRUGS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002068456-A1 | ECHINOCANDIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE THEREOF AS DRUGS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-06 | — | — | WO | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082757-A1 | Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs | MAN2B1, MAN2A1, ALG1 | NR5A1 516/4885L3MBTL1 3513/4885TDP1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.