SCHEMBL990609

SCHEMBL990609

CCCCOCc1cc[c]cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
LTA4H P09960 2/20 0.36
NR5A1 Q13285 1/20 0.36
TSHR P16473 4/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 1/20 0.36
HPGD P15428 1/20 0.35
P2RX7 Q99572 1/20 0.35
PLA2G4B P0C869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7299873 0.96 TSHR (0.40) L3MBTL1TDP1LTA4HNR5A1TSHR
SCHEMBL7003091 0.94 NR5A1 (0.39) L3MBTL1TDP1LTA4HNR5A1PLA2G4B
SCHEMBL6999535 0.92 NR5A1 (0.42) L3MBTL1TDP1LTA4HNR5A1ALDH1A1
SCHEMBL6540133 0.92 NR5A1 (0.42) L3MBTL1TDP1LTA4HNR5A1ALDH1A1
SCHEMBL9688098 0.91 MEN1 (0.41) L3MBTL1TDP1LTA4HNR5A1TSHR
SCHEMBL9687974 0.89 MEN1 (0.44) L3MBTL1TDP1NR5A1TSHRALDH1A1
SCHEMBL5958235 0.88 TSHR (0.36) L3MBTL1TDP1LTA4HTSHR
SCHEMBL647523 0.85 L3MBTL1 (0.49) L3MBTL1TDP1LTA4HNR5A1TSHR
SCHEMBL7296533 0.84 NAAA (0.35) L3MBTL1TSHR
SCHEMBL7304240 0.82 ALDH1A1 (0.44) TSHRALDH1A1CYP3A4MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107846898-B Diphenyl methanol derivatives for management of hypoxia inducible factor related disorders 佐治亚州立大学研究基金会 2023-07-14 CN disclosed
CN-107846898-A Diphenylcarbinol derivatives for the management of hypoxia inducible factor-related conditions 佐治亚州立大学研究基金会 2018-03-27 CN disclosed
US-9112081-B2 Sealing film for solar cell and solar cell obtained by use of the sealing film BRIDGESTONE CORPORATION (JP) 2015-08-18 US disclosed
CN-101960616-B Sealing film for solar cell and solar cell using same BRIDGESTONE CORP 2013-12-18 CN disclosed
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
CN-101960616-A Sealing film for solar cell and solar cell using same BRIDGESTONE CORP 2011-01-26 CN disclosed
US-20110005592-A1 SEALING FILM FOR SOLAR CELL AND SOLAR CELL OBTAINED BY USE OF THE SEALING FILM BRIDGESTONE CORPORATION (JP) 2011-01-13 US disclosed
EP-2259331-A1 SEALING FILM FOR SOLAR CELLS AND SOLAR CELL USING THE SAME Bridgestone Corporation (JP) 2010-12-08 EP disclosed
CN-101668767-A Pyridine derivatives substituted with heterocyclic ring and phosphonoamino group and antifungal agent containing the same EISAI R&D MAN CO LTD 2010-03-10 CN disclosed
EP-0120463-B1 ANTHRAQUINONE DYES AND LIQUID CRYSTAL COMPOSITIONS INCLUDING THE SAME HITACHI, LTD. (JP) 1991-11-06 EP disclosed
EP-0400519-A1 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them Dr. Karl Thomae GmbH (DE) 1990-12-05 EP disclosed
EP-0072932-B1 PIPERAZINONES, THEIR PREPARATION AND USE CASSELLA Aktiengesellschaft (DE) 1990-01-17 EP disclosed
EP-0098736-B1 ANTHRAQUINONE DYES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE DYES MITSUBISHI KASEI CORPORATION (JP) 1989-12-06 EP disclosed
US-4610804-A Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1986-09-09 US disclosed
US-4598079-A MEMORY DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1986-07-01 US disclosed
US-4507221-A Anthraquinone dye and liquid crystal composition containing the same MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-03-26 US disclosed
EP-0120463-A2 Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1984-10-03 EP disclosed
EP-0098736-A2 Anthraquinone dyes and liquid crystal compositions containing the dyes MITSUBISHI KASEI CORPORATION (JP) 1984-01-18 EP disclosed
EP-0072932-A2 Piperazinones, their preparation and use CASSELLA Aktiengesellschaft (DE) 1983-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 L3MBTL1 779/4885TDP1 3862/4885LTA4H 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.