Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.55 |
| ▸ | ABCC8 | Q09428 | 7/20 | 0.55 |
| ▸ | KCNJ11 | Q14654 | 7/20 | 0.55 |
| ▸ | KCNJ8 | Q15842 | 7/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539913 | 0.88 | ESR1 (0.46) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6541437 | 0.88 | ESR1 (0.46) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6540898 | 0.86 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6540415 | 0.84 | CNR1 (0.40) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6540853 | 0.84 | ESR1 (0.42) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6799811 | 0.84 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6552531 | 0.84 | ESR1 (0.46) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6540797 | 0.84 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6540648 | 0.83 | ABCB11 (0.41) | ABCC9ABCC8KCNJ11KCNJ8ESR1 | |
| SCHEMBL6810020 | 0.83 | ABCB11 (0.41) | ABCC9ABCC8KCNJ11KCNJ8ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ABCC9 1823/4885ABCC8 629/4885KCNJ11 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.