Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539412 | 0.92 | MTNR1A (0.45) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6277656 | 0.90 | PPARD (0.39) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6539856 | 0.89 | MTNR1A (0.48) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6539805 | 0.89 | MTNR1A (0.44) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6539756 | 0.85 | MTNR1A (0.44) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6539064 | 0.85 | MTNR1A (0.42) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6539042 | 0.85 | MTNR1A (0.42) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6539778 | 0.81 | KDM4E (0.42) | ALDH1A1MTNR1AMTNR1BPPARDKMT2A | |
| SCHEMBL6254853 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 | |
| SCHEMBL6539622 | 0.81 | MTNR1A (0.44) | ALDH1A1MTNR1AMTNR1BHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | ALDH1A1 163/4885MTNR1A 410/4885MTNR1B 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.