Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | BACE1 | P56817 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539376 | 1.00 | MAOB (0.77) | MAOBRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8723038 | 0.84 | MAOB (0.71) | MAOBRAB9ANPC1PKMNFKB1 | |
| SCHEMBL6540328 | 0.84 | MAOB (0.56) | MAOBRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL6208376 | 0.82 | F3 (0.68) | MAOBRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL9839473 | 0.81 | KDM4E (0.66) | MAOBRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL9837797 | 0.81 | KDM4E (0.66) | MAOBRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL9839479 | 0.81 | KDM4E (0.66) | MAOBRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL11372251 | 0.80 | GSK3B (0.62) | MAOBRAB9ANPC1SMN1; SMN2ABCG2 | |
| SCHEMBL791985 | 0.79 | MAOB (0.69) | MAOBRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL17237521 | 0.79 | MAOB (0.62) | MAOBRAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | MAOB 397/4885RAB9A 4006/4885NPC1 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.